Tag Archives: Plant Extraction

The topic of plant extraction may be research topic and hence, all the topics or contents related to plant extraction cannot be included in this description

However, enough insight will be provided by categorizing the plant extraction into various groups that are easy to understand and absorb from a general view point. There will not be much technical information contained in this. However, many important points will be listed to know the very basics of plant extraction.

The plant extraction is broadly classified into the following seven categories for the purpose of this article:

  • Plant extraction – Oils
  • Plant extraction – From vegetables
  • Plant extraction – From fruits
  • Plant extraction – Dyes
  • Plant extraction – Herbal
  • Plant extraction – Cosmetic products and
  • Plant extraction – From roots

Even we use the plants and plant products directly in our day-to-day life, we do use the plant extraction in a limited quantity. For instance, one may not use all the above listed extraction altogether. One may use the oil extracts in large quantities in food industries, whereas the dye extracts may be widely used in garment or some chemical industry. Herbal, root and medicinal extracts are mainly used in healthcare or medical fields. Fruits and vegetables extracts play a vital role sometimes in helping to nourish the body parts, internal or external.

The plant products such as leaves, vegetables or fruits are generally taken in large quantities. However, plant extraction are taken in proportions when compared to the actual fruit or vegetable. The dictionary definition for extract is ‘to remove from a larger whole’. It can also be referred to as essence or concentrate. The extract is a concentrated portion from the large vegetable mass, such as the plant extraction of sugar cane juice from the sugar cane plant, leaving the fodder aside and the juice in a glass. The juice is referred here as the extract. Let us now explore the different types of plant extraction.

 

An Example for API manufacturing

There are several types of API manufacturing in present days

Almost every antidote which is biologically synthesized contains Active Pharmaceutical Ingredient in it. There are used in almost every field of pharmacy and especially in herbal treatment. One such example is Gemfibrozil API manufacturing which is a drug used for lowering lipid levels. Lipids are fat layers present under the skin which determines the amount of cholesterol present in our body. People who are obese are prescribed to take this API. It belongs to the drug family of fibrates and this API is manufactured.

This API is an activator of Peroxisome  proliferator-activated receptor – alpha (PPARA) which is a nuclear receptor related directly to the synthesis of carbohydrates and fat. It is proven to be effective in adipose tissue differentiation.

When taken as recommended it results in the reduction of triglyceride levels and very low lipoprotein (VLDL) and a reduction of a less magnitude of LDL levels. It results in the level increase of high-density lipoprotein (HDL) levels. Normal medication dosage of gemfibrozil is 600 mg a short while after breakfast.

Some precautions while taking these drugs are given here. Those who are suffering from kidney failure must not take this.

People with diabetes must also avoid this because intake of these drugs may lead to a rise in insulin levels. This drug may lead to side effects like gallstones, hypokalemia and even cancer also. So these drugs are better to be avoided in case of a longer medication situation.    

Like Gemfibrozil, there are several kinds of API manufacturing like Venlafaxine which is used as an anti-depressant, Carbidopa API manufacturing which is used for the treatment of Parkinson’s disease which affects the key areas of the brain, Diltiazem API which is used for cardiovascular diseases and many more. These make the pharmaceutical industry go leaps and bounds in curing millions of people.   

Plant Extraction: A Brief Overview of the Process

The process of plant extraction is achieved with the help of another process that inolves the extraction of solid liquids.

To make this process more understandable, we can define it simply as the process in which various compounds are being separated by solubilization from a solid form body with the help of a chemical agent called solvent. This process is later completed with a method called the purification method. If there is an edible solvent present in the extract, then it is not dissociated. If there is an inedible solvent present in the extract, a dry extract is obtained from it with the help of the separation process.

Quality Parameters:

 

  • The main factors that contribute to plant extraction include equipment that performs well, selection of raw materials, utilization process, and the choice of quality solvents.
  • High quality plant extraction can only be achieved by professionally and properly combining various quality parameters.

 

Plant Integrity Conservation

Plant extraction methods result in better plant integrity conservation. This occurs due to the mere fact that administration methods become multiplied with the help of new plant properties discovery. The result of that is the meeting of customers’ needs. Because of that, high quality and new technological equipment needs to be introduced. That allows the ability of quality extracts being provided together with a personalized solution which meets with client’s expectations. This kind of plant integrity conservation becomes an essential conservation.

About Plant Extracts

Whenever we talk about plant extracts, what image we should have in mind is simple powders which were made thanks to the crushing and the processing of plants. These powders that were crushed from the plants and later on processed are called on the market extracts. They are being called extracts because they do not contain not even 1% of water. Water is however used in their making but it is later on eliminated thanks to the drying process from the plants.

Before separation method takes place, one special process needs to take place. What is that process being called? The name of that special process that needs to be utilized before separation is extraction. This process is also known by many as plant extraction. Common raw plants help this process become successful. Plant extraction produces liquid from the initial solid form. Speaking of purification process, the solubilization step has to be added to it. If a desired ingredient needs to be extracted from a liquid form body, a process called pressing needs to be performed. The extract that needs to be extracted from the liquid form can be extracted with solid-liquid extraction process. What comes next after this process is purification process.

Plant extraction- Advantages and Challenges of Formulating Drugs

 

In order to ensure that high potency drugs deliver notable results, they undergo a process known as encapsulation. In most cases, the formulation of drugs is from substances that are mainly plant extraction from different parts of the world. We can define this process as the enclosing of tiny droplets in a coating to form capsules. Each capsule contains the correct percentage of drug that a patient needs for proper execution of its intended purpose. Encapsulation has been widely used in the manufacture of multivitamins and drugs. Plant extraction is a process that has been used worldwide from ancient times in order to extract medical values from plants and herbs.

 

Why is it important to encapsulate drugs?

 

  • Production costs are highly cut down.
  • Reduced risk of drug-human contamination
  • Drug-drug contamination is also reduced
  • Reduced production time
  • Handling them is easier as compared to other methods
  • The chances of an explosion or fire are reduced.

 

As the need for drugs keeps on rising, so are the challenges. Some of the challenges are:

 

First, the medicine is becoming expensive by the day. The number of qualified plant operators is diminishing as a result of the high qualifications that have been set out. Upgrading of the safety measures requirements has also resulted in the low production of the drugs. This follows the manufacturer’s inability to comply in time.

 

Waste disposal measures and equipment to aid the same have become too expensive. Perhaps, this is because of a rise in demand due to the upcoming manufacturers. Regulators have taken it upon themselves to make requirements strict enough in order to curb unscrupulous manufacturers.

 

There are several challenges that are faced by pharmaceutical companies while plant extraction process are going on.

 

What can be done?

 

In retaliation of these challenges, manufacturers should ensure they comply with the laid down rules. They should carry out extensive screening of their employees to ensure they do not have half-baked plant operators.
Manufacturers need to have good record skills and if need be, they can upgrade to software and applications to aid in the safe delivery of good quality high potency drugs.

Plant extraction a methodical approach, know it here

Plant extraction refers to a substance or the desirable active properties that are removed from the plant

tissues or a plant tissue. This is usually done by treating the plant with a solvent so that may be useful for

practical purposes.

Use of plant extraction

 Plant extraction may be useful in various sectors such as food and functional properties as

texturizer or antioxidant.

 It may be used in additives, pharmaceutical for preventive or curative types of therapeutic

properties or even for functional or cosmetic properties that promotes well-being and beauty.

Cosmetic use

The plant extraction is defined for cosmetic uses such as it is used for hair system, epidermis, lips, nails

and external organs or with the teeth, the oral cavity, changing appearance, perfuming or correcting body

odors or eve safeguarding them and maintaining them in proper conditions.

Plant extraction or any other extract is common, but differs with each sector depending on its chemical

needs and description. Though different sectors show different forms and different technologies are used

based on the stability and solubility, different claims, different regulation and unique problems are

experienced. Thus the manufacturers take good care so that the end users are not troubled and the product

is adaptable.

Qualification of plant extract

Plant extraction is being done for various purposes and the methods also vary as per the demand. A plant

extract should also respect:

 The constraints of quality with respect to allergens, irradiation, activity, adulteration, toxicity,

stability, activity, traceability, sustainable resources, etc.

 The physical and chemical request with respect to the description such as physical recognition,

TLC, genotype and also as nitrates, heavy metals, solvents, residues such as pesticides, additives

or foreign bodies.

 The regulation is with respect to the solvent, legal uses, environmental conditions and

components, labeling, claims, registration or organic grades, certification, etc.

Plant extraction of Essential Oils and its methods

Plant extraction is being done from a long time to extract essential oils employed in aromatherapy.

These are extracted from barks, plants leaves, roots and flowers. The procedure employed to extract

essential oil from the plant material is referred to as distillation. This distillation process is lengthy, but

ascertains the oil extraction without affecting the quality.

Extracting of plant oils

Distillation refers to extracting the component from the liquid through the heating and condensation

process. It results in complete separation and increases the selected components concentration mixture.

Distillation completes separation of components and based on the mixture it may be partial as well.

Plant extraction methods

 Water and steam are taken together and this help in plant extraction as the oil is pushed out of

the plant. Thus essential oil is accumulated leaving behind the steam.

 Plant extraction is also done by placing the plant extracts in a container covered ensuring the

steam does not evaporate. Thus the plant extracts are steamed before it starts giving out oil. It is

important to have a control on the temperature so that enough extracts are released to get essential

oil. This is a cumbersome process as from tons of plant materials only small amount of oil gets

extracted.

Complex structure

All the plants feature complex structure. The plant extraction process for multiple compounds or any

particular compound depends on the solubility and the extraction media such as organic solvent, water or

organic solvents mixture using the physical separation principle and the solubility property of the

compounds in the extraction media.

The plant design and the process of plant extraction system are different with each products and

component. It is difficult to generalize and extract from various herbs the isolated compounds. This is

because everything involves a series of processes and the rich compounds are extracted in a generalized

manner, while the next stage involves purification and isolation.

Fluid Extraction Steps From Plant Extraction

Plant extraction is to separate different required minerals from the predefined gasp so one needs to

set up a general structure strong fluid extraction. The contact stage relates to the mass exchange

step. There are different strides to accomplish complete plant extraction. The principal period of

division can't be separated from the contact stage since it empowers isolating the utilized strong

from the advanced dissolve-able solvent, as a rule by straightforward filtration. At this stage, the

concentrate is contained in the dissolve-able solvent.

On the off chance that the dissolve-able solvent is eatable, it is not important to continue to a second

detachment that expels the dissolve-able solvent and leaves a dry concentrate. The case of coffee,

presumably the most-expended concentrate in Europe, delineates this procedure.

Coffee, which is considered as the crude material is placed in contact with water in a percolator at a

specific temperature and for a specific period of time. The primary separation is finished with a

paper channel or filter, which empowers drinking the espresso/refined coffee specifically. On the off

chance that we do another partition, we get coffee at hand and enjoy in our daily life.

Some of the fluid extraction steps from plant extraction are detailed here;

 Maceration, where the contact stage is kept up at room temperature

 Decoction, where the contact stage is kept up at the bubbling temperature of the dissolve-

able solvent.

 Digestion, where the contact stage is kept up at a temperature between the initial two

temperatures.

 Infusion, where bubbling dissolve-able solvent is poured over the strong and is left to cool

for a specific period of time.

 Lixiviation or permeation, where the dissolve-able solvent goes through the biomass.

Aside from the instance of squeezing, where elements of fluid birthplace are extricated, a concentrate is

gotten just from a strong fluid of plant extraction, which might be trailed by cleaning.