Tag Archives: solvent extraction plant

Plant extraction- Advantages and Challenges of Formulating Drugs


In order to ensure that high potency drugs deliver notable results, they undergo a process known as encapsulation. In most cases, the formulation of drugs is from substances that are mainly plant extraction from different parts of the world. We can define this process as the enclosing of tiny droplets in a coating to form capsules. Each capsule contains the correct percentage of drug that a patient needs for proper execution of its intended purpose. Encapsulation has been widely used in the manufacture of multivitamins and drugs. Plant extraction is a process that has been used worldwide from ancient times in order to extract medical values from plants and herbs.


Why is it important to encapsulate drugs?


  • Production costs are highly cut down.
  • Reduced risk of drug-human contamination
  • Drug-drug contamination is also reduced
  • Reduced production time
  • Handling them is easier as compared to other methods
  • The chances of an explosion or fire are reduced.


As the need for drugs keeps on rising, so are the challenges. Some of the challenges are:


First, the medicine is becoming expensive by the day. The number of qualified plant operators is diminishing as a result of the high qualifications that have been set out. Upgrading of the safety measures requirements has also resulted in the low production of the drugs. This follows the manufacturer’s inability to comply in time.


Waste disposal measures and equipment to aid the same have become too expensive. Perhaps, this is because of a rise in demand due to the upcoming manufacturers. Regulators have taken it upon themselves to make requirements strict enough in order to curb unscrupulous manufacturers.


There are several challenges that are faced by pharmaceutical companies while plant extraction process are going on.


What can be done?


In retaliation of these challenges, manufacturers should ensure they comply with the laid down rules. They should carry out extensive screening of their employees to ensure they do not have half-baked plant operators.
Manufacturers need to have good record skills and if need be, they can upgrade to software and applications to aid in the safe delivery of good quality high potency drugs.

Plant extraction a methodical approach, know it here

Plant extraction refers to a substance or the desirable active properties that are removed from the plant

tissues or a plant tissue. This is usually done by treating the plant with a solvent so that may be useful for

practical purposes.

Use of plant extraction

 Plant extraction may be useful in various sectors such as food and functional properties as

texturizer or antioxidant.

 It may be used in additives, pharmaceutical for preventive or curative types of therapeutic

properties or even for functional or cosmetic properties that promotes well-being and beauty.

Cosmetic use

The plant extraction is defined for cosmetic uses such as it is used for hair system, epidermis, lips, nails

and external organs or with the teeth, the oral cavity, changing appearance, perfuming or correcting body

odors or eve safeguarding them and maintaining them in proper conditions.

Plant extraction or any other extract is common, but differs with each sector depending on its chemical

needs and description. Though different sectors show different forms and different technologies are used

based on the stability and solubility, different claims, different regulation and unique problems are

experienced. Thus the manufacturers take good care so that the end users are not troubled and the product

is adaptable.

Qualification of plant extract

Plant extraction is being done for various purposes and the methods also vary as per the demand. A plant

extract should also respect:

 The constraints of quality with respect to allergens, irradiation, activity, adulteration, toxicity,

stability, activity, traceability, sustainable resources, etc.

 The physical and chemical request with respect to the description such as physical recognition,

TLC, genotype and also as nitrates, heavy metals, solvents, residues such as pesticides, additives

or foreign bodies.

 The regulation is with respect to the solvent, legal uses, environmental conditions and

components, labeling, claims, registration or organic grades, certification, etc.

Plant extraction of Essential Oils and its methods

Plant extraction is being done from a long time to extract essential oils employed in aromatherapy.

These are extracted from barks, plants leaves, roots and flowers. The procedure employed to extract

essential oil from the plant material is referred to as distillation. This distillation process is lengthy, but

ascertains the oil extraction without affecting the quality.

Extracting of plant oils

Distillation refers to extracting the component from the liquid through the heating and condensation

process. It results in complete separation and increases the selected components concentration mixture.

Distillation completes separation of components and based on the mixture it may be partial as well.

Plant extraction methods

 Water and steam are taken together and this help in plant extraction as the oil is pushed out of

the plant. Thus essential oil is accumulated leaving behind the steam.

 Plant extraction is also done by placing the plant extracts in a container covered ensuring the

steam does not evaporate. Thus the plant extracts are steamed before it starts giving out oil. It is

important to have a control on the temperature so that enough extracts are released to get essential

oil. This is a cumbersome process as from tons of plant materials only small amount of oil gets


Complex structure

All the plants feature complex structure. The plant extraction process for multiple compounds or any

particular compound depends on the solubility and the extraction media such as organic solvent, water or

organic solvents mixture using the physical separation principle and the solubility property of the

compounds in the extraction media.

The plant design and the process of plant extraction system are different with each products and

component. It is difficult to generalize and extract from various herbs the isolated compounds. This is

because everything involves a series of processes and the rich compounds are extracted in a generalized

manner, while the next stage involves purification and isolation.

Fluid Extraction Steps From Plant Extraction

Plant extraction is to separate different required minerals from the predefined gasp so one needs to

set up a general structure strong fluid extraction. The contact stage relates to the mass exchange

step. There are different strides to accomplish complete plant extraction. The principal period of

division can't be separated from the contact stage since it empowers isolating the utilized strong

from the advanced dissolve-able solvent, as a rule by straightforward filtration. At this stage, the

concentrate is contained in the dissolve-able solvent.

On the off chance that the dissolve-able solvent is eatable, it is not important to continue to a second

detachment that expels the dissolve-able solvent and leaves a dry concentrate. The case of coffee,

presumably the most-expended concentrate in Europe, delineates this procedure.

Coffee, which is considered as the crude material is placed in contact with water in a percolator at a

specific temperature and for a specific period of time. The primary separation is finished with a

paper channel or filter, which empowers drinking the espresso/refined coffee specifically. On the off

chance that we do another partition, we get coffee at hand and enjoy in our daily life.

Some of the fluid extraction steps from plant extraction are detailed here;

 Maceration, where the contact stage is kept up at room temperature

 Decoction, where the contact stage is kept up at the bubbling temperature of the dissolve-

able solvent.

 Digestion, where the contact stage is kept up at a temperature between the initial two


 Infusion, where bubbling dissolve-able solvent is poured over the strong and is left to cool

for a specific period of time.

 Lixiviation or permeation, where the dissolve-able solvent goes through the biomass.

Aside from the instance of squeezing, where elements of fluid birthplace are extricated, a concentrate is

gotten just from a strong fluid of plant extraction, which might be trailed by cleaning.